GENIE Analysis

This repository contains code used to generate figures for the Project GENIE manuscript "AACR Project GENIE: 100,000 cases and beyond".

Main figures

3. Virtual trial matching - Tali Mazor, James Lindsay, Priti Kumari, DFCI

4. Actionable and resistant mutations - Michelle Green and Jonathan Bell, DUKE

5. Driver mutations in rare cancers - Stephen-John Sammut, Gary Doherty, CRUK

Supplemental figures

3. Gene-level mutation frequencies in GENIE versus TCGA - Matthew Galvin, Brady Bernard, PROV

4. Summary of gene-level mutation frequencies - Matthew Galvin, Brady Bernard, PROV

5. Tumors without drivers - Jeff Bruce, UHN

6. Tumor mutation burden by contributing center and by cancer subtype - Haley Hunter-Zinck, Sage Bionetworks