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module-3-reproducible-research-and-data-analysis's Introduction

Module 3: Reproducible Research and Data Analysis

Rationale

Reproducible research is at the heart of science. There has been an increased need and willingness to open and share research from the data collection right through to the interpretations of results. This has come with its own set of challenges, which include designing workflows that can be adopted by collaborators in a way that does not compromise the integrity of their contribution. This module will introduce the necessary tools required for transparent reporting which is reproducible and readable.

Learning outcomes

  1. Researchers will be able to describe the key factors that affect the reproducibility of research, including workflow design, data management, and reporting.
  2. The researcher will be able to use a range of resources to create and implement a workflow for reproducible research, including using lab notebooks and tools for sharing code and data.

Development team

TBC

Key documents

Code of conduct

All modules of the Open Science MOOC are released with a Contributor Code of Conduct. By participating in this project you agree to abide by its terms.

Licenses

Content

MOOC content license: CC0 Public Domain Dedication

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module-3-reproducible-research-and-data-analysis's Issues

GETTING REPRODUCIBLE , from nature blog, food for thoughts?

(Copied from Module 5, #39 by @jcolomb there)

From https://www.nature.com/articles/d41586-018-05990-5, while it is more for module 3 on data analysis, there is probably a connection.
just wondering...

Use code. Instead of pointing and clicking, use programming languages to download, filter, process and output your data, and command-line scripts to document how those tools are executed.

Go open-source. Code transparency is key to reproducibility, so use open-source tools whenever possible. “If you give me a black box with no source code and it just gives me numbers, as far as I am concerned, it’s a random-number generator,” says mathematician Les Hatton of Kingston University in London.

Track your versions. Using version-control software such as Git and GitHub, researchers can document and share the precise version of the tools that they use, and retrieve specific versions as necessary.

Document your analyses. Use computational notebooks such as Jupyter to interleave code, results and explanatory text in a single file.

Archive your data. Freeze data sets at key points — when submitting an article for publication, for example — with archiving services such as Zenodo, Figshare or the Open Science Framework.

Replicate your environment. Software ‘containers’, such as Docker, bundle code, data and a computing environment into a single package; by unboxing it, users can recreate the developer’s system. ReproZip, developed in the lab of New York University computer scientist Juliana Freire, simplifies container creation by watching program execution to identify its requirements. The commercial service Code Ocean and an open-source alternative, Binder, enable researchers to create and share executable Docker containers that users can explore in a web browser.

Automate. Automation provides reproducibility without users really having to think about it, says bioinformatician Casey Greene at the University of Pennsylvania in Philadelphia. Continuous integration services such as Travis CI can automate quality-control checks, for instance, and the Galaxy biocomputing environment automatically logs details of the jobs it runs.

Get help. Resources abound for interested researchers; see practicereproducibleresearch.org, for instance, or find a Software Carpentry workshop near you to learn basic computing skills.

Examples of Open Science practices to add

  • To report studies, analyses and results completely
  • A prior planning of sufficient sample size, preferabley on the basis of power analyses
  • To make the results of unsuccessful replications of fundings of other persons (or own findings) available using online resources
  • To participate in the replication and examination of published findings, as far as the circumstances allow you to do so
  • To make data, materials, and analysis protocols online available at the time of publication
  • Preregistration of hypotheses of studies (or declare study as explicitly exploratory)

Source: https://github.com/OpenScienceMOOC/Module-1-Open-Principles/blob/master/Reading%20Material_Open%20Principles/St%C3%BCrmer%20et%20al.%2C%202017.pdf

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