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License: MIT License
Computational identification of targets for CAR-T cell therapy in AML
License: MIT License
Great work and thank you for providing such detailed code!
I am curious on how you chose the threshold when filtering out genes based on expression in your COOTA data clusters? Specifically, how you chose the 2% threshold?
And, was there any optimization of this threshold in terms of what minimal expression in vital cell types would be deemed "safe"?
Thanks
Dear Professors,
Congratulations! Great work on NBT! I am interested in the scRNA-seq-based screening algorithm of your published manuscript. According to your code, I installed “sfaira” package but found that some code (sfaira.data.human.DatasetGroupKidney) did not work. I want to know which version of "sfaira" used in your data procession? And could you provide the processed h5ad file of the single cell data across multiple organs? Thank you very much for your kindly help!!!
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