This is the github repository to store all analysis code for the project
A framework for detecting causal effects of risk factors at an individual level based on principles of Mendelian randomization: Applications to modelling individualized effects of lipids on coronary artery disease
Also termed as MR-ITE.
Code Structure:
- 01_simulation: codes for simulation on ITE inference and heterogeneity testing.
- 02_data_preprocessing: code for preprocessing the UKBB related data.
- 03_pleiotropy_removal: code for performing pleiotropical SNPs removal using conmix approach.
- 04_prs_calculation: code for calculating the PRS using PRSice-2.
- 05_ivgrf_disease: code for ITE inference on UKBB dataset.
- 06_visualization_tablesummary: code for visualization and summarization of the results.