This repository provides raw data for Brugia molting motif analysis. Please see our pre-print:
Grote Alexandra, Yichao Li, Canhui Liu, Denis Voronin, Adam Geber, Sara Lustigman, Thomas Unnasch, Lonnie Welch, and Elodie Ghedin. Prediction pipeline for discovery of regulatory motifs associated with Brugia malayi molting. bioRxiv (2019): 781930.
Raw motif discovery results were provided in folders such as L3D6_L3
, which means up-regulated genes in L3D6 comparing to L3. Each folder also contains the fasta sequences (i.e., fore.fa
and back.fa
) used to perform motif analysis. Motif analysis was done using Emotif_alpha
Genome features and orthologs info were provided in genome_data
.
There were 395 motifs passed our statistical tests, shown in Brugia_molting_motifs.merged.pwm
.
There were 12 motifs out of those 395 motifs that were conserved in either C. elegans or O. volvulus, shown in Supp_File_motif_PWM.meme