This is an R package for performing STAAR procedure in whole genome sequencing studies.

STAAR is an R package for performing variant-Set Test for Association using Annotation infoRmation (STAAR) procedure in whole genome sequencing studies. STAAR is a general framework that incorporates both qualitative functional categories and quantitative complementary functional annotations using an omnibus multi-dimensional weighting scheme.

R (recommended version >= 3.4.2)

For optimal computational performance, it is recommended to use an R version configured with the Intel Math Kernel Library (or other fast BLAS/LAPACK libraries). See the instructions on building R with Intel MKL.

STAAR links to R packages Rcpp and RcppArmadillo, and also imports R packages Rcpp, GMMAT, GENESIS, Matrix. These dependencies should be installed before installing STAAR.

library(devtools)
devtools::install_github("xihaoli/STAAR")

Please see the user manual for detailed usage of STAAR package.

The current version is 0.9.3 (August 12, 2019).

This software is licensed under GPL-3.