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biotea-box's Introduction

BioTEA-box

This repository hosts the code for the BioTEA Docker container. The container runs the analysis itself.

The BioTEA repo contains the guides and extra information on the tool. Click here to go to it

Installation

You do not need to install BioTEA-Box locally. BioTEA takes care of that for you. Please check that repository instead.

Issues

Have an issue with the box? File a new issue! Be as detailed as you can so we can solve the issue quickly. Also check out bioTEA's issues: your problem may have already been submitted.

Have a question about BioTEA? Send an issue in the main repository.

Contributing

Check the CONTRIBUTING.md file if you want to contribute.

biotea-box's People

Contributors

feat-fear avatar mrhedmad avatar

biotea-box's Issues

Restructure Annotation Procedure

This issue was raised by @Feat-FeAR :

The internal annotations for human chips do not have linked scripts for re-generation. Additionally, there are other considerations to make:

  • Many Agilent microarrays do not have annotations as bioconductor packages, but only as GEO GPL accessions. This should be addressed by adding annotations for all Agilent arrays.
  • The annotated columns as gene symbols should be surpassed by ENSG when possible. This has all the benefits of using ENSGs instead of gene names, plus it better supports RNA-Seq, which by default is annotated with ENSGs in most pipelines.

Generalize expression matrix first column name

Currently, the name of the first column of the expression matrix loaded by read_expression_data() is hard-coded to be "probe_id"... this is fragile and conceptually incorrect for a probe-independent technology like RNA-Seq. We should remove such a constraint.

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