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Leo's Projects

infercna icon infercna

Infer Copy Number Alterations and Clonality in (Single-Cell) RNA-Seq Data

kelvinny icon kelvinny

Kelvin's R package that holds wrapper functions for a number of work things

ktplots icon ktplots

Some tools for plotting single-cell data

leukemia-paper icon leukemia-paper

Analysis code and data for leukemia paper (preliminary title: Single cell mRNA signals reveal a distinct developmental state of KMT2A-rearranged infant B-lymphoblastic leukaemia)

luad_mirna_bayesianml icon luad_mirna_bayesianml

R code for synergetic LUAD miRNA signature analysis with Bayesian inference and machine learning approach

machine-learning-on-breast-cancer-survival-prediction icon machine-learning-on-breast-cancer-survival-prediction

We used different machine learning approaches to build models for detecting and visualizing important prognostic indicators of breast cancer survival rate. This repository contains R source codes for 5 steps which are, model evaluation, Random Forest further modelling, variable importance, decision tree and survival analysis. These can be a pipeline for researcher who are interested to conduct studies on survival prediction of any type of cancers using multi model data.

maier_et_al_nature_2020 icon maier_et_al_nature_2020

This repository contains scripts used for analysis and figure generation in Maier, B., Leader, A.M., Chen, S.T. et al. A conserved dendritic-cell regulatory program limits antitumour immunity. Nature 580, 257–262 (2020). https://doi.org/10.1038/s41586-020-2134-y

mars icon mars

Discovering novel cell types across heterogenous single-cell experiments

metamarkers icon metamarkers

Efficiently compute robust markers across single-cell datasets

mmcp-counter icon mmcp-counter

Murine version of MCP-counter, a tool to estimate the immune and stromal composition of heterogeneous tissue, from transcriptomic data

movics icon movics

Multi-Omics integration and VIsualization in Cancer Subtyping

multisurv icon multisurv

Multimodal deep learning model for long-term cancer survival prediction

neoantigenml icon neoantigenml

This is an neoantigens filtering repository by machine learning method

nmd-paper icon nmd-paper

A pan-cancer genome-wide analysis reveals tumour dependencies by induction of nonsense-mediated decay

phenograph icon phenograph

Subpopulation detection in high-dimensional single-cell data

pisces icon pisces

R package for Protein activity analysis of single-cell RNAseq.

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