Automated analysis pipeline for long-read sequencing and an information system to store and present results. These tools are focused on use in a clinical setting and are currently applied to BCR-ABL1 TKI resistance mutation screening for patients undergoing treatment for chronic myeloid leukemia and related diseases.

CLAMP consists of separate parts for sequence data processing (clamp-calc) and informatics (clamp-gui). While designed to work in unison, installation and usage will be explained separately since they are possibly installed on separate systmes and used by different people.

Data processing:

• Calc Installation
• Calc Processing
• Reporting

Results:

• GUI Installation
• GUI usage

Copyright 2022 Pincer Bio AB
CLAMP is available under the terms of Apache 2.0 Licence.

This work has been published:
Wesley Schaal, Adam Ameur, Ulla Olsson-Strömberg, Monica Hermanson, Lucia Cavelier, Ola Spjuth.
"Migrating to Long-Read Sequencing for Clinical Routine BCR-ABL1 TKI Resistance Mutation Screening"
Cancer Informatics, 2022.
https://doi.org/10.1177/11769351221110872