The procedure of determining the optimal quantization steps for a single decomposition can be extrapolated to the quantization of a sequence of images transformed by the MDWT and the MCDWT. In this case, (and always supposing that only 2 spatial resolution levels will be available, that is the same that to say that MDWT has been applied only one time) instead of considering 4 subbands in the optimization, you must consider all the subbands of the optimized GOP, that are (except for the first GOP) 4*2^T, where T is the number of iterations of the MCDWT.
GOP 0 GOP 1
------- ---------------
img 0 img 2
+--+--+ +--+--+
|LL|LH| |LL|LH|
+--+--+ +--+--+
|HL|HH| |HL|HH|
+--+--+ +--+--+
a c
img 1
+--+--+
|LL|LH|
+--+--¡
|HL|HH|
+--+--+
~
b
there are 3 images, to which the MDWT and the one-iterations (T=1) MCDWT has been applied (a, b and c are the alias of the images in the forward MCDWT butterfly). As can be seen, there are 4*2^1 = 8 subbands in the GOP 1 (the first GOP always has only one image). So, the quantization step optimizer should consider 8 RD curves (instead of only 4) in the GOP 1.