GeneCodeq utilises coding theory as a foundation and uses available evidence under a Bayesian statistical model to adjust quality scores in genomic datasets, leading to substantial improvements in compressibility of these datasets.
GeneCodeq can be used on 64bit versions of Linux, Mac and Windows. Please consult the wiki pages for more information on setting up GeneCodeq for your system.
GeneCodeq uses a command line interface to perform adjustment of quality scores of sequence reads in fastq/sam file formats. Please consult the wiki pages (Using GeneCodeq) for more details.
GeneCodeq uses the approach as described in a paper submitted to Bioinformatics to perform adjustment of quality scores. Please consult the paper for more details. The title of the submitted version of the paper is 'GeneCodeq: quality score compression and improved genotyping using coding theory'.
The wiki pages contain detailed information about the evaluation of GeneCodeq. Source code directories: src - contains miscellaneos tools that have been used for GeneCodeq evaluation scripts - contains scripts that were used for genotyping analysis
Please use GitHub issues to open bug reports or provide feedback about GeneCodeq.