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Extracellular vesicle-derived miRNA-mediated cell-cell communication inference for single-cell transcriptomic data

Home Page: https://github.com/multitalk/awesome-cell-cell-communication

License: GNU General Public License v3.0

R 2.11% HTML 97.89%
cell-cell-communication cell-cell-interaction extracellular-vesicles mirna scrna-seq-data single-cell-rna-seq exosomes microvesicles

mirtalk's Issues

Questions about the number of microRNAs

To developers

miRTalk is an interesting work, but I have some doubts. What do you think of the fact that it is almost difficult to detect micro RNA in the 10X data. According to 10X genomic, almost no mature micro RNA can be detected in the data (Ref 1-2). As in the Demo data, only 60+ micro RNAs were detected in the end.

Ref 1-2:
https://kb.10xgenomics.com/hc/en-us/articles/360002004271-Is-it-possible-to-capture-microRNAs-in-the-Gene-Expression-assays-
https://kb.10xgenomics.com/hc/en-us/articles/217261666-What-types-of-RNA-can-be-detected-

with regards,
Xinyan Yang

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