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View Code? Open in Web Editor NEWA phantom bursting mechanism for episodic bursting (Bertram et al 2008)
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A phantom bursting mechanism for episodic bursting (Bertram et al 2008)
Home Page: https://modeldb.science/247646
<html> The models for the paper:<p/> A phantom bursting mechanism for episodic bursting, R. Bertram, J. Rhoads and W.P. Cimbora, 2008, Bulletin of Mathematical Biology, 70, 1979-1993. <p/> PubMed ID: 18648884<p/> <a href="http://dx.doi.org/10.1007/s11538-008-9335-0">doi: 10.1007/s11538-008-9335-0</a> <p/> are available in xpp at the authors web site:<p/> <a href="https://www.math.fsu.edu/~bertram/software/neuron/">https://www.math.fsu.edu/~bertram/software/neuron/</a><p/> After starting the BMB_08b.ode, and then for second graph BMB_08b_noisy.ode below in xpp select Initalconds -> Go to generate these images:<p/> <img src="./screenshot1.png" alt="screenshot 1"><p/> <img src="./screenshot2.png" alt="screenshot 2"><p/> <p/> and the noise-less version is available at cellml.org:<p/> <a href="https://models.cellml.org/exposure/48e767ee37f347e1a3876d0549a0866b/bertram_2008.cellml/view">https://models.cellml.org/exposure/48e767ee37f347e1a3876d0549a0866b/bertram_2008.cellml/view</a><p/> After loading the bertram_2008.cellml.xml in opencor, right click the membrane voltage in the parameter panel and select to plot against either integration variable (top plot), or s2 (buried in Plot against -> ls2 -> s2 -> s2):<p/> <img src="./screenshot3.png" alt="screenshot 3" width="650"><p/> It reproduces figure 4, where g_K1 = 20pS </html>
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