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Stochastic model of the olfactory cilium transduction and adaptation (Antunes et al 2014)

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151686's Introduction

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This is the readme for the model associated with the paper:
<p/>
Antunes G, Sebastiao AM, Simoes de Souza FM (2014) Mechanisms of
regulation of olfactory transduction and adaptation in the olfactory
cilium. PLoS One 9:e105531
<p/>
This model was contributed by Fabio Marques Simoes de Souza.
<p/>
COPASI, free software, is required for this model and is available,
along with documentation, from <a href="http://www.copasi.org/">http://www.copasi.org/</a>
  <p/>
  Example Usage:<br/>
  --------------<br/>
  Start COPASIUI and open model_treatment.cps. Select Time Course and click on Run. You should see a graph of Ca2+ generated:<p/>
  <img src="./screenshot1.png" alt="screenshot">
  <p/>
  The figures in the paper are the mean results from hundreds 
of single runs. The screen shot reproduces a single 
run of the model. Supplementary figure S3, first column (A to E) shows 
the example of 5 single runs. The first column of Fig. S3 panel F shows 
the mean result of hundred simulations. We used the Condor Copasi 
  platform to do it automatically:
  <a href="https://www.nimml.org/tools/copasi-suite/condor-copasi">https://www.nimml.org/tools/copasi-suite/condor-copasi</a>
(There is a similar relationship between model_control.cps and supplementary figure 2).
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