mirams / sine-wave Goto Github PK
View Code? Open in Web Editor NEWCode for training and validation of ion channel models fitted to sine-wave based voltage clamp data
License: BSD 3-Clause "New" or "Revised" License
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Redo Kylie's exact procedure
Check the matlab code, reimplement, summarise in text form
Do for before and after signal, then subtract to get dofetilide subtracted one
Determine EK from sine wave crossings
E.g. using smoothing spline to find crossings during sine portion of the signal
The links for redoing figure 3 in the readme file are broken
Apply Chon method to sine wave data 9 cells
Fit simultaneously to -80 and -120 step using I_leak = g_leak * (V - E_leak)
Do for before and after signal, then subtract to get dofetilide subtracted one
Summarise in text form
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