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Genetic algorithm for automated PK/PD model selection
Hey,
Thanks for all the work in providing this application. However, I think it might still be quite difficult to use for people not used to R programming. I'm trying to get the application to work based on the examples in the paper, but am running into some issues.
Some of the things that are not immediately obvious:
should be coded as:
tokengroup, tokenset, token
model, mySet, "thing I want in PK for this Set"
model, mySet, "thing I want in THETA for this Set"
model, myOtherSet, "thing I want in PK for this Set"
model, myOtherSet, "thing I want in THETA for this Set"
tokengroup, tokenset, token
WTonCL, one_param, THETA([1]) * WT
WTonCL, one_param, (0, 1); param1 WTonCL
WTonCL, many params, THETA([1]) * WT**THETA([2]) - THETA([3])
WTonCL, many params, (0, 1); param #1 \newline (0, 1); param #2 \newline (0, 1); param #3 \newline
Imagine the \newline actually being newlines.
Is this correct synthax? Will the THETA([i]) etc take the ith index from the second token? How does it know that it should take the index from that token?
I do not see this behaviour working correctly in the 'Preview' window as of now.
I guess some documentation on how to setup the alltokens.csv in general would be useful.
Error: cannot open the connection
. In R I see the following error popping up:
Cannot open file GAgens.csv: no such file or directory.
This makes sense as that file does not exist. However, it is never generated in the application. I can create it manually (with a Generation, Individual, and Dir column), but then it complains about there not being any lines with information in the file.
(when clicking the View Models button, it similarily complains about allmodsResults.csv.gz
)
This raises the question: How are you actually supposed to initialize the program? How do you run the model? I have a ctl file and alltokens.csv, but I guess I need to prepare more files?
Hope you can help with providing this information!
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