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Bayesian predictive model for personalized treatment selection for new untreated patients, which leverages known predictive and prognostic biomarkers. In particular, predictive biomarkers are exploited to inform a product partition model with covariates (PPMx) to obtain homogeneous clusters.

R 38.35% C++ 60.75% C 0.90%
bayesian-inference nonparametricbayes precision-medicine r-package

treatppmx's Introduction

treatppmx

CRAN status Lifecycle: stable

An R package for personalized treatment selection at a single decision point.

Bayesian predictive model for personalized treatment selection for new untreated patients, which leverages known predictive and prognostic biomarkers. In particular, predictive biomarkers are exploited to inform a product partition model with covariates (PPMx) to obtain homogeneous clusters.

The implementation has been done in C++ through the use of Rcpp and RcppArmadillo.

Authors: Matteo Pedone, Raffaele Argiento, Francesco Stingo

Maintainer: Matteo Pedone.

Installation

You can install the development version of treatppmx from GitHub with:

# install.packages("devtools")
devtools::install_github("mattpedone/treatppmx")

NOTE that this package depends on vweights.

# install.packages("devtools")
devtools::install_github("mattpedone/vweights")

It has only been tested on a PC running Ubuntu 20.04.2 LTS.

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