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View Code? Open in Web Editor NEWAjusted local kernel smoothing for bisulfite sequencing data
Ajusted local kernel smoothing for bisulfite sequencing data
AKSmooth ======== Ajusted local kernel smoothing for low-coverage bisulfite sequencing data. 1. INSTALL # Download and unzip this file, and run the following codes in R: install.packages("devtools") library(devtools) # Find the directory where AKSmooth-master file is located and set the following new working directory. setwd("./AKSmooth-master") # Load the package into memory load_all() # Install the package install() 2. USAGE # After installation one can reload the AKSmooth package. library(AKSmooth) # Example load("./data/bn1chr21.rda") data <- bn1chr21 fitChr21gau <- AKSmooth(data, 30, "Gaussian") # For more details. ?AKSmooth Reference Chen, J., Lutsik, P., Akulenko, R., Walter, J., & Helms, V. (2014). AKSmooth: Enhancing low-coverage bisulfite sequencing data via kernel-based smoothing. Journal of bioinformatics and computational biology, 12(06), 1442005.
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