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reprogram-seq's Introduction

Reprogram-Seq

DOI

Reprogram-Seq leverages organ-specific cell atlas data with single-cell perturbation and computational analysis to predict, evaluate, and optimize TF combinations that reprogram a cell type of interest.


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Code

To reproduce results:

Citation

Jialei Duan#, Boxun Li#, Minoti Bhakta#, Shiqi Xie, Pei Zhou, Nikhil V. Munshi*, Gary C. Hon* (2019). Rational Reprogramming of Cellular States by Combinatorial Perturbation. Cell Rep. 27, 3486โ€“3499.e6.
DOI: http://dx.doi.org/10.1016/j.celrep.2019.05.079


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reprogram-seq's Issues

data files missing in the directory data

Subdirectory "epicardial_10f_d7" and "epicardial_3f_d7" and related rds files are not found in the current edition under the directory "data/10x" in this project, would you please update these files?

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