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I compiled and installed ReliefSeq on an Ubuntu 12.04 system that has Boost and OpenMPI libraries installed. The program ran successfully using the --dge-counts-data option as outlined on the web page (http://insilico.utulsa.edu/ReliefSeq.php), although the screen output said it would use 24 threads and the 'top' command showed only one processor used by the reliefseq process. When I try using a PLINK-covariate-file-format input file with the -n option, and a phenotype file specified by the -a option, the program output again says the program will use all 24 available cores, but hangs and does nothing for hours. Is there a way to test the program to make sure it compiled correctly to give access to the openmpi libraries?

I compiled Reliefseq last summer and had it running on a Ubuntu 12.04 system, then did not use it for a while. In the meantime, the system was upgraded to Ubuntu 14.04. When I tried Reliefseq again, it complained "error while loading shared libraries: libboost_program_options.so.1.46.1"
The upgraded system has Boost 1.47, but I thought perhaps not all Boost libraries had been upgraded, so I ran apt-get install libboost-all-dev to make sure all libraries were updated (several packages were installed, so that seemed to have been worthwhile). After that I removed the previously-compiled version of Reliefseq, cloned the Github repo, and set BOOST_ROOT to /usr/local/include/boost, then ran bootstrap.sh and configure, both of which seemed to complete without problems. When I run make, however, things go wrong after a while. What seems to me to be the last command executed is pasted below, followed by a series of error messages about boost_program_options. The output from ./configure indicated that the BOOST_PROGRAM_OPTIONS variables were set without issues, so I'm not sure how to proceed.

"/bin/bash ./libtool --tag=CXX --mode=link g++ -I. -I/usr/local/include/boost/include -fopenmp -O3 -Wall -I/usr/local/include -g -O2 -fopenmp -L/usr/local/lib -L/usr/local/Cellar/gcc/4.9.2_1/lib/gcc/4.9 -lgomp -o reliefseq ReliefSeqCLI.o Insilico.o DistanceMetrics.o Statistics.o Dataset.o ArffDataset.o PlinkDataset.o PlinkBinaryDataset.o PlinkRawDataset.o DgeData.o BirdseedData.o DatasetInstance.o AttributeRanker.o ChiSquared.o ReliefF.o RReliefF.o SNReliefF.o ReliefFSeq.o ReliefSeqController.o -L/usr/local/lib -L/usr/local/Cellar/gcc/4.9.2_1/lib/gcc/4.9 -lgomp -lgsl -lgslcblas -lboost_program_options -L. -lgomp
libtool: link: g++ -I. -I/usr/local/include/boost/include -fopenmp -O3 -Wall -I/usr/local/include -g -O2 -fopenmp -o reliefseq ReliefSeqCLI.o Insilico.o DistanceMetrics.o Statistics.o Dataset.o ArffDataset.o PlinkDataset.o PlinkBinaryDataset.o PlinkRawDataset.o DgeData.o BirdseedData.o DatasetInstance.o AttributeRanker.o ChiSquared.o ReliefF.o RReliefF.o SNReliefF.o ReliefFSeq.o ReliefSeqController.o -L/usr/local/lib -L/usr/local/Cellar/gcc/4.9.2_1/lib/gcc/4.9 -lgsl -lgslcblas -lboost_program_options -L. -lgomp -fopenmp
ReliefSeqCLI.o: In function std::basic_string<char, std::char_traits<char>, std::allocator<char> > const& boost::program_options::validators::get_single_string<char>(std::vector<std::basic_string<char, std::char_traits<char>, std::allocator<char> >, std::allocator<std::basic_string<char, std::char_traits<char>, std::allocator<char> > > > const&, bool)': /usr/local/include/boost/include/boost/program_options/detail/value_semantic.hpp:58: undefined reference toboost::program_options::validation_error::validation_error(boost::program_options::validation_error::kind_t, std::string const&, std::string const&)'
/usr/local/include/boost/include/boost/program_options/detail/value_semantic.hpp:62: undefined reference to boost::program_options::validation_error::validation_error(boost::program_options::validation_error::kind_t, std::string const&, std::string const&)' ReliefSeqCLI.o:(.rodata._ZTVN5boost16exception_detail19error_info_injectorINS_15program_options20invalid_option_valueEEE[_ZTVN5boost16exception_detail19error_info_injectorINS_15program_options20invalid_option_valueEEE]+0x20): undefined reference toboost::program_options::validation_error::what() const'
ReliefSeqCLI.o:(.rodata._ZTVN5boost16exception_detail10clone_implINS0_19error_info_injectorINS_15program_options20invalid_option_valueEEEEE[_ZTVN5boost16exception_detail10clone_implINS0_19error_info_injectorINS_15program_options20invalid_option_valueEEEEE]+0x20): undefined reference to boost::program_options::validation_error::what() const' ReliefSeqCLI.o:(.rodata._ZTVN5boost16exception_detail19error_info_injectorINS_15program_options16validation_errorEEE[_ZTVN5boost16exception_detail19error_info_injectorINS_15program_options16validation_errorEEE]+0x20): undefined reference toboost::program_options::validation_error::what() const'
ReliefSeqCLI.o:(.rodata._ZTVN5boost16exception_detail10clone_implINS0_19error_info_injectorINS_15program_options16validation_errorEEEEE[_ZTVN5boost16exception_detail10clone_implINS0_19error_info_injectorINS_15program_options16validation_errorEEEEE]+0x20): undefined reference to boost::program_options::validation_error::what() const' ReliefSeqCLI.o:(.rodata._ZTVN5boost15program_options20invalid_option_valueE[_ZTVN5boost15program_options20invalid_option_valueE]+0x20): undefined reference toboost::program_options::validation_error::what() const'
collect2: error: ld returned 1 exit status
make[1]: *** [reliefseq] Error 1
make[1]: Leaving directory `/home/ross/software/reliefseq'
make: *** [all] Error 2"