This library implements elastic grid-based deformations for N-dimensional images.

The elastic deformation approach is described in

• Ronneberger, Fischer, and Brox, "U-Net: Convolutional Networks for Biomedical Image Segmentation" (https://arxiv.org/abs/1505.04597)
• Çiçek et al., "3D U-Net: Learning Dense Volumetric Segmentation from Sparse Annotation" (https://arxiv.org/abs/1606.06650)

The procedure generates a coarse displacement grid with a random displacement for each grid point. This grid is then interpolated to compute a displacement for each pixel in the input image. The input image is then deformed using the displacement vectors and a spline interpolation.

In addition to the normal, forward deformation, this package also provides a function that can backpropagate the gradient through the deformation. This makes it possible to use the deformation as a layer in a convolutional neural network. For convenience, a TensorFlow wrapper is provided in elasticdeform.tf.

pip install elasticdeform
or
pip install git+https://github.com/gvtulder/elasticdeform

This library requires Python 3 and NumPy development headers.

On Windows, try to install the precompiled binaries directly using pip install elasticdeform. If that does not work, these precompiled packages might be an alternative option.

This basic example deforms an image with a random 3 x 3 deformation grid:

import numpy, imageio, elasticdeform
X = numpy.zeros((200, 300))
X[::10, ::10] = 1

# apply deformation with a random 3 x 3 grid
X_deformed = elasticdeform.deform_random_grid(X, sigma=25, points=3)

imageio.imsave('test_X.png', X)
imageio.imsave('test_X_deformed.png', X_deformed)

If you have multiple images, e.g., an image and a segmentation image, you can deform both simultaneously by providing a list of inputs. You can specify a different spline order for each input.

# apply deformation to inputs X and Y
[X_deformed, Y_deformed] = elasticdeform.deform_random_grid([X, Y])

# apply deformation to inputs X and Y,
# with a different interpolation for each input
[X_deformed, Y_deformed] = elasticdeform.deform_random_grid([X, Y], order=[3, 0])

By default, a deformation will be applied to every dimension of the input. If you have multi-channel images, you can use the axis parameter to specify which axes should be deformed. The same deformation will be applied for each channel.

For example, to deform an RGB image across the first two dimensions, run:

X_deformed = elasticdeform.deform_random_grid(X, axis=(0, 1))

When deforming multiple inputs, you can provide a tuple of axes for each input:

X = numpy.random.rand(3, 200, 300)
Y = numpy.random.rand(200, 300)
[X_deformed, Y_deformed] = elasticdeform.deform_random_grid([X, Y], axis=[(1, 2), (0, 1)])

If you intend to crop a small subpatch from the deformed image, you can provide the crop dimensions to the deform function. It will then compute only the cropped output pixels, while still computing the deformation grid based on the full image dimensions. This saves computation time.

X = numpy.random.rand(200, 300)

# define a crop region
crop = (slice(50, 150), slice(0, 100))

# generate a deformation grid
displacement = numpy.random.randn(2, 3, 3) * 25

# deform full image
X_deformed = elasticdeform.deform_grid(X, displacement)
# compute only the cropped region
X_deformed_crop = elasticdeform.deform_grid(X, displacement, crop=crop)

# the deformation is the same
numpy.testing.assert_equal(X_deformed[crop], X_deformed_crop)

The deform_grid_gradient function can be used to backpropagate the gradient of the output with respect to the input. Call deform_grid_gradient with the parameters that were used for the forward step.

X = numpy.random.rand(200, 300)

# generate a deformation grid
displacement = numpy.random.randn(2, 3, 3) * 25

# perform forward deformation
X_deformed = elasticdeform.deform_grid(X, displacement)

# obtain the gradient w.r.t. X_deformed (e.g., with backpropagation)
dX_deformed = numpy.random.randn(*X_deformed.shape)

# compute the gradient w.r.t. X
dX = elasticdeform.deform_grid_gradient(dX_deformed, displacement)

Note: The gradient function will assume that the input has the same size as the output. If you used the crop parameter in the forward phase, it is necessary to provide the gradient function with the original, uncropped input shape in the X_shape parameter.

The elasticdeform.tf module provides a wrapper for deform_grid in TensorFlow. The function uses TensorFlow Tensors as input and output, but otherwise uses the same parameters.

import numpy
import elasticdeform.tf as etf

displacement_val = numpy.random.randn(2, 3, 3) * 5
X_val = numpy.random.rand(200, 300)
dY_val = numpy.random.rand(200, 300)

# construct TensorFlow input and top gradient
displacement = tf.Variable(displacement_val)
X = tf.Variable(X_val)
dY = tf.Variable(dY_val)

# the deform_grid function is similar to the plain Python equivalent,
# but it accepts and returns TensorFlow Tensors
X_deformed = etf.deform_grid(X, displacement, order=3)

# the gradient w.r.t. X can be computed in the normal TensorFlow manner
[dX] = tf.gradients(X_deformed, X, dY)

This library was written by Gijs van Tulder at the Biomedical Imaging Group Rotterdam, Erasmus MC, Rotterdam, the Netherlands

It is inspired by a similar, Python-based implementation by Florian Calvet. This C-based implementation gives the same results, but is faster and has a gradient implementation.

This C implementation includes a modified version of the NI_GeometricTransform from SciPy's ndimage library.

This code is made available under the BSD license. See LICENSE.txt for details.

• https://github.com/gvtulder/elasticdeform
• https://elasticdeform.readthedocs.io/