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Easylearn is designed for machine learning mainly in resting-state fMRI, radiomics and other fields (such as EEG). Easylearn is built on top of scikit-learn, pytorch and other packages. Easylearn can assist doctors and researchers who have limited coding experience to easily realize machine learning, e.g., (MR/CT/PET/EEG)imaging-marker- or other biomarker-based disease diagnosis and prediction, treatment response prediction, disease subtyping, dimensional decoding for transdiagnostic psychiatric diseases or other diseases, disease mechanism exploration and etc.