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crsky's Projects

siglasso icon siglasso

Optimizing Cancer Mutation Signatures Jointly with Sampling Likelihood

signac icon signac

An analytics package for single cell data

sigprofilerextractor icon sigprofilerextractor

SigProfilerExtractor allows de novo extraction of mutational signatures from data generated in a matrix format. The tool identifies the number of operative mutational signatures, their activities in each sample, and the probability for each signature to cause a specific mutation type in a cancer sample. The tool makes use of SigProfilerMatrixGenerator and SigProfilerPlotting.

single-cell-tutorial icon single-cell-tutorial

Single cell current best practices tutorial case study for the paper:Luecken and Theis, "Current best practices in single-cell RNA-seq analysis: a tutorial"

singler icon singler

SingleR: Single-cell RNA-seq cell types Recognition (legacy version)

skylab icon skylab

Soon to be deprecated in favor of broadinstitute/warp github repo. Previously: Secondary analysis pipelines

soupx icon soupx

R package to quantify and remove cell free mRNAs from droplet based scRNA-seq data

spotlight icon spotlight

Spatial Transcriptomics Capture Location Deconvolution

swne icon swne

Similarity Weighted Nonnegative Embedding (SWNE), a method for visualizing high dimensional datasets

ted icon ted

a fully Bayesian approach to deconvolve tumor microenvironment

tidyverse icon tidyverse

Easily install and load packages from the tidyverse

tiedie icon tiedie

Tied Diffusion for Subnetwork Discovery (TieDIE)

topometry icon topometry

A comprehensive dimensional reduction framework to recover the latent topology of high-dimensional data.

tweedieverse icon tweedieverse

Differential analysis of multi-omics data based on the Tweedie distribution

unifan icon unifan

Unsupervised cell functional annotation for single-cell RNA-Seq

vcf2maf icon vcf2maf

Convert a VCF into a MAF, where each variant is annotated to only one of all possible gene isoforms

vision icon vision

Signature Analysis and Visualization for Single-Cell RNA-seq

warp icon warp

WDL Analysis Research Pipelines

xcell icon xcell

Cell types enrichment analysis

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