Calculation of the MARKER-HF heart failure risk score from E. Adler et al, Improving risk prediction in heart failure using machine learning Eur J Heart Fail. doi:10.1002/ejhf.1628 (2020).

The calculation of MARKER-Hf is also available through a web calculator.

MARKER-HF is calculated based on the following eight covariates within the specified ranges:

• Diastolic pressure (mm Hg) [20-120]
• Creatinine (mg/dL) [0-25]
• Blood Urea Nitrogen (mg/dL) [0-160]
• Hemoglobin (g/dL) [2-20]
• White Blood Cell Count (1e3 μL) [0-40]
• Platelets (1e3 μL) [0-1500]
• Albumin(g/dL) [0-6]
• Red Blood Cell Distribution Width (%) [10-30]

Code to calculate MARKER-HF and the one year or 90 days survival probabilities (aka 1-Mortality) is available in either C++ or python from the two standalone folders. The python version is probably easier to use.

Note: in the C++ folder there are instructions on how to build the executable for MacOS and Linux, as well as precompiled binaries for WIndows.