cljs-exe is a Boot template to create a Clojurescript application that will compile to a native binary using nexe.

nexe, on which this project is based, lists these reasons:

• Ability to run multiple applications with different node.js runtimes.
• Distributable binaries without needing node / npm.
• Starts faster.
• Lockdown specific application versions, and easily rollback.
• Faster deployments.

I'll second those and add: "In ClojureScript."

You will need

• Boot
• NodeJS
• Python somewhere on your path (it is an nexe dependency)

$ brew install boot-clj
$ boot -d boot/new new -S -t cljs-exe -n your_project_name
$ cd your_project_name
$ boot package

This will compile some sample Clojurescript code to Javascript, then compiling the Javascript to a native binary.

This project template gives you a few boot tasks:

• build: runs the Clojurescript compiler with defaults that include: fetching npm dependencies that are listed in the js-dependencies var in build.boot, emitting source maps, and no compiler optimizations.
• dev: runs build in a watch loop, rerunning build anytime you change a source file.
• binary: compiles the current project Javascript into a native binary on your platform.
• package: compiles Clojurescript to Javascript with simple compiler optimizations and no source maps, then compiles that Javascript to a native binary on your platform.