This repo has the necessary files to reproduce the analysis on the boolean model presented in Gupta et al. (2018), titled 'Modeling the role of microRNA-449a in the regulation of the G2/M cell cycle checkpoint in prostate LNCaP cells under ionizing radiation'. The present reproducibity analysis was the project of the PhD course Logical Modeling for Experimental Design in Current and Future Biotechnology and Biomedicine, offered by NTNU during the Autumn of 2018.

First, you need to install the colomoto-docker. Then:

git clone https://github.com/bblodfon/colomotoGupta.git
cd pathTo/colomoto-docker
python colomoto_docker.py -V 2018-08-17 --bind /pathTo/colomotoGupta

The gupta_john_zobolas.ipynb is the main notebook file.