Comments (4)
from poped.
Hi Andrew,
If I keep those three points 120 120 120 hours, how can I implement this scheme? Three sampling points are all located at 120 hours. At a specific time point, we can sample only one time.
Thank you,
Sibo
from poped.
from poped.
Hi Andrew,
Based on the above discussion, three approaches might be applicable to this scenario. My respective questions are:
1. Specification a restriction about how often sampling can occur.
At this time point, is there any built-in function of PopED to implement this?
2. Random sampling within a window around the optimal point.
In the official tutorial, there are two identical points: 10 and 10 hours. With a half hour gap, an intuitive window could be 9.75/10.25 hours, 10/10.5 hours or 9.5/10 hours. How do you think of this scheme?
3 Include information about correlation of parameters.
I am now on the way of learning the paper you cited.
I am sorry to ask so many questions. There’s no hurry to respond at once. I am happy to wait。
Sibo
from poped.
Related Issues (20)
- Manually updating the number of samples as an alternative to opt_samps in R? HOT 1
- Plotting optimized output seems to used wrong times HOT 1
- Where is the optimization parallelized HOT 3
- unused argument in plot_model_prediction() HOT 2
- parallel computation for plot_efficiency_of_windows() HOT 4
- problem with tests run by AppVeyor HOT 2
- Warning "Problems inverting the matrix. Results could be misleading." HOT 2
- Different results when running the optimization R-script in popED in Windows and Mac HOT 2
- Integrating an IV loading dose followed by SC maintenance dose using popEd HOT 1
- Illogical OFV when xts have a lot of significant digits HOT 2
- D-optimal Design for a trial comparing three different drugs
- Design Evaluation when No. of subjects change towards the end of trial HOT 6
- Gradient function HOT 2
- Handling derived outputs
- `evaluate_fim_map` documentation
- Error in svd(mat) : infinite or missing values in 'x'
- Define a model with lag time HOT 5
- Take an example of the pk.3.comp.olal.ode model
- multiple dose full TMDD model in POPED HOT 3
- Two questions HOT 3
Recommend Projects
-
React
A declarative, efficient, and flexible JavaScript library for building user interfaces.
-
Vue.js
🖖 Vue.js is a progressive, incrementally-adoptable JavaScript framework for building UI on the web.
-
Typescript
TypeScript is a superset of JavaScript that compiles to clean JavaScript output.
-
TensorFlow
An Open Source Machine Learning Framework for Everyone
-
Django
The Web framework for perfectionists with deadlines.
-
Laravel
A PHP framework for web artisans
-
D3
Bring data to life with SVG, Canvas and HTML. 📊📈🎉
-
Recommend Topics
-
javascript
JavaScript (JS) is a lightweight interpreted programming language with first-class functions.
-
web
Some thing interesting about web. New door for the world.
-
server
A server is a program made to process requests and deliver data to clients.
-
Machine learning
Machine learning is a way of modeling and interpreting data that allows a piece of software to respond intelligently.
-
Visualization
Some thing interesting about visualization, use data art
-
Game
Some thing interesting about game, make everyone happy.
Recommend Org
-
Facebook
We are working to build community through open source technology. NB: members must have two-factor auth.
-
Microsoft
Open source projects and samples from Microsoft.
-
Google
Google ❤️ Open Source for everyone.
-
Alibaba
Alibaba Open Source for everyone
-
D3
Data-Driven Documents codes.
-
Tencent
China tencent open source team.
from poped.