This repository is a sort of "plugin" for denovogear.
It adds the mutmap
command to dng
, which allows the generation of an HTML
file which contains an interactive visualization.
Copy everything in this repository (except this README file) into the root of your denovogear repository.
You also need to add the following line to src/CMakeLists.txt
:
add_subdirectory(mutmap)
There are also some runtime dependencies. You'll need to have R installed
(specifically the Rscript
command), along with the R libraries listed in
src/mutmap/tools/install_r_dependencies.R
.
Once everything is in place, rebuild and install denovogear. You should now
have the dng mutmap
command available.
You need 2 things to generate the visualization file:
- A VCF file as output from a denovogear run
- A corresponding ped file for the pedigree matching the VCF
Then you can run something like the following:
dng mutmap -p PED_FILE.ped -d DNG_OUTPUT_FILE.vcf -o mutmap.html
You should then be able to open the mutmap.html file in any modern browser to see the visualization. Note that currently the entire contents of the VCF file is included in the HTML file, so it can be quite large and take a bit of time to load, especially if you host the HTML file over the internet. This has only been tested with a ~20MiB file so far.