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PPiMapBuilder

PPiMapBuilder is a Cytoscape 3 app for protein-protein interaction network generation and protein-protein interaction prediction via the Phylogenetic profiling method as described by:

Echeverría PC, Bernthaler A, Dupuis P, Mayer B, Picard D (2011) An interaction network predicted from public data as a discovery tool: application to the Hsp90 molecular chaperone machine. PLoS One 6: e26044.doi:10.1371/journal.pone.0026044.

PPiMapBuilder uses PSICQUIC services to retrieve interaction data, InParanoid 8 for protein orthology and UniProt for protein data.

This project was initiated by Pablo Echeverría from picardLab as a bio-informatic master student project.

To get more details about this Cytoscape 3 app, you can check the wiki.

PPiMapBuilder ScreenShot

Installation

From release

  1. Download the lastest PPiMapBuilder release
  2. Install PPiMapBuilder-X.X.jar
  • Within Cytoscape:
    • Go to Apps > App Manager
    • Click Install from file
    • Select the PPiMapBuilder jar file

OR

  • Manually:
    • Move the PPiMapBuilder jar file to <USER_DIRECTORY>/CytoscapeConfiguration/3/apps/installed/

From source code

  1. Clone this git repository or download source
  2. Run mvn install in the PPiMapBuilder folder
  3. Install ./target/PPiMapBuilder-X.X.jar
  • Within Cytoscape:
    • Go to Apps > App Manager
    • Click Install from file
    • Select the PPiMapBuilder jar file

OR

  • Manually:
    • Move the PPiMapBuilder jar file to <USER_DIRECTORY>/CytoscapeConfiguration/3/apps/installed/

Reference webservices used

UniProt PSICQUIC UniProt UniProt UniProt

ppimapbuilder's Projects

ppi-query icon ppi-query

Protein-protein interaction network (with orthology) querying library

ppimapbuilder icon ppimapbuilder

Cytoscape 3.0 app. Generation of protein-protein interaction network with prediction using protein orthology

ppimapbuilderforcy2.8 icon ppimapbuilderforcy2.8

Cytoscape 2.8 plug-in. Generation of protein-protein interaction network with prediction using protein orthology

ppiretriever icon ppiretriever

Server-side software filling the PPiMapBuilder (for Cy 2.8) database

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