Download 1,000 Random Human RefSeq Transcripts about edirectcookbook HOT 2 OPEN

I am assuming that you are interested in fetching sequences in FASTA format.
I suggest you download a file with all transcript sequences in FASTA format for a specific genome assembly's latest annotation using NCBI Datasets and then use a program like seqkit to extract n random sequences from the file.
EntrezDirect is not the most efficient way to download data in bulk. But if you don't have a choice, one way to achieve something like this would be to: (1) get a list of all accessions using a combination of esearch and efetch -format acc, (2) use a Unix tool like sort -R or shuf to extract n random accessions, then (3) use a combination of epost and efetch to download sequences in FASTA format.

from edirectcookbook.

Very helpful. Thank you! I downloaded the GRC38 patch Patch 14 transcripts, extracted just the accession
numbers, randomized the result using shuf, and then downloaded the corresponding records via efetch.

from edirectcookbook.