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swillems avatar swillems commented on August 16, 2024

Hey @hanghu1024 . Thanks for your interest in using AlphaTims. I actually have not tried AlphaTims without IMS (the "tims" part of the name was added for a reason of course). That said, it might be compatible with you data with little modification if we are lucky. Could you share a data file with me so that I can check out of I can get this to work?

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hanghu1024 avatar hanghu1024 commented on August 16, 2024

Hello @swillems, you can get that data file in this link: https://drive.google.com/drive/folders/1c7yZsjoQai1sudRDSWNjtUbdc3zz7x5H?usp=sharing
Thank you so much for the wonderful work, really appreciate it!

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swillems avatar swillems commented on August 16, 2024

Dear @hanghu1024, thanks for sharing the data. I have checked it out, but unfortunately it would require more time to make that format compatible with AlphaTims than I currently have available. At first glance, the issue is not so much the fact that there is no mobility, but that you use a .tsf instead of .tdf with an alternative binary format that AlphaTims currently is unable to read. I have not tested this myself, but you might want to try out TIMSCONVERT to process these files (e.g. by converting them to mzml that should be a generic input for many other tools).

We might include .tsf support in the future, but this is not on any of our plannings yet...

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hanghu1024 avatar hanghu1024 commented on August 16, 2024

Hello @swillems Thank you so much! I tries some codes in timsconvert, it works for .tsf data.

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