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Jin's Projects

18s191 icon 18s191

Course 18.S191 at MIT, fall 2020 - Introduction to computational thinking with Julia:

3dtumorsimulator icon 3dtumorsimulator

simulated the spatiotemporal dynamics of a multicellular tumor using a three-dimensional (3D) agent-based model, in which the cells in the tumor are represented as interacting objects. In this model, the cells grow stochastically as a function of time and divide upon reaching a critical size. The cell-to-cell interaction is characterized by direct elastic and adhesive forces. We also consider cell-to-cell and cell-to-matrix damping as a way of accounting for the effects of friction experienced by a moving cell because of other cells and by the extracellular matrix (ECM) (or collagen matrix), respectively. Each cell is modeled as a deformable sphere with a time-dependent radius. Several physical properties, such as the radius, elastic modulus, membrane receptor and ligand concentration, and adhesive interaction, characterize each cell.

ads1-notebooks icon ads1-notebooks

Copies of notebooks used in the practical sessions for Algorithms for DNA Sequencing

bad-data-guide icon bad-data-guide

An exhaustive reference to problems seen in real-world data along with suggestions on how to resolve them.

bumpy icon bumpy

Quick tutorial of scientific computing with Python using a real physics application.

cancertypeprediction icon cancertypeprediction

This is the repository for paper titled as "Convolutional neural network models for cancer type prediction based on gene expression".

colon_cancer_parameter_estimation_sensitivity_analysis icon colon_cancer_parameter_estimation_sensitivity_analysis

Codes for parameter estimation and sensitivity analysis of QSP models for colon cancer. This is a part of the National Cancer Institute funded project titled "Data-driven QSP software for personalized colon cancer treatment" Achyuth Manoj, Susanth Kakarla, Suvra Pal and Souvik Roy.

covid19-qsp-model icon covid19-qsp-model

Open Source QSP model describing SARS-CoV-2 virus and host cell life cycles, immune response and therapeutic treatments

cpt_qsptutorial icon cpt_qsptutorial

Supplementary material for CPT tutorial on logic modeling for quantitative systems pharmacology

dnds-clonesize icon dnds-clonesize

Snakemake pipeline to produce figures for "Measuring the distribution of fitness effects in somatic evolution by combining clonal dynamics with dN/dS ratios"

dynamicmodeling icon dynamicmodeling

These are MATLAB code I wrote while having Coursera Course Dynamic Modeling Methods for System Biology

evoldynamics1 icon evoldynamics1

A 4-compartment (which can be egeneralized to higher compartments) was studied to understand the phenotypic heterogeneity in modeling cancer evolution.

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