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adaptivedesigninterface

A collection of S4 functions to interface with trial design objects from various packages.

adestr

Point estimates, confidence intervals and p-values for adaptive two-stage designs with planned adaptivity.

adoptr

Adaptive optimal two-stage designs for clinical trials made easy.

cubature

Cubature R Package

descrtab2

This package provides functions to create descriptive statistics tables for continuous and categorical variables.

mvtnorm

:exclamation: This is a read-only mirror of the CRAN R package repository. mvtnorm — Multivariate Normal and t Distributions. Homepage: http://mvtnorm.R-forge.R-project.org

optimalgoldstandarddesigns

Methods to calculate optimal design parameters for one- and two-stage three-arm group-sequential gold-standard non-inferiority trial designs with or without binding or nonbinding futility boundaries.

riskmetric

Metrics to evaluate the risk of R packages

rmathextended

Rmath, various other R functions and mvtnorm bundled in a single CMake project

rocker-versioned2

statistische-methoden-des-maschinellen-lernens

uncoupledisoreg

This R package implements the algorithm proposed by Rigollet & Weed in their 2019 paper to solve the uncoupled isotonic regression problem.

valtools

Validation framework for R packages used in clinical research and drug development.