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Hylke's Projects

liftover_plink_beds icon liftover_plink_beds

Converting UK Biobank genome-wide genotyping data from one reference build to another

pomegranate icon pomegranate

Fast, flexible and easy to use probabilistic modelling in Python.

pyvcf icon pyvcf

A Variant Call Format reader for Python.

sigprofilerassignment icon sigprofilerassignment

Mutational signature attribution and decomposition tool with custom inclusion and exclusion rules

sigprofilermatrixgenerator icon sigprofilermatrixgenerator

SigProfilerMatrixGenerator creates mutational matrices for all types of somatic mutations. It allows downsizing the generated mutations only to parts for the genome (e.g., exome or a custom BED file). The tool seamlessly integrates with other SigProfiler tools.

vcfpy icon vcfpy

Python 3 library with good support for both reading and writing VCF

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