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Gillian McHugo 🐄🧬💻

Computational biology PhD researcher at University College Dublin studying integrative genomics of infectious diseases in cattle, focusing on trypanosomiasis in hybrid African cattle and bovine tuberculosis in Irish cattle.

gillianmchugo.github.io orcid.org/0000-0001-6920-0041

Publications

Kelly, P. A., McHugo, G. P., Scaife, C., Peters, S., Stevenson, M. L., McKay, J. S., MacHugh, D. E., Saez, I. L., & Breathnach, R. (2024). Unveiling the role of endoplasmic reticulum stress pathways in canine demodicosis. Parasite Immunology, 46(4), e13033. doi:10.1111/pim.13033.

Ward, J. A., Ng’ang’a, S. I., Randhawa, I. A. S., McHugo, G. P., O’Grady, J. F., Flórez, J. M., Browne, J. A., Pérez O’Brien, A. M., Landaeta-Hernández, A. J., Garcia, J. F., Sonstegard, T. S., Frantz, L. A. F., Salter-Townshend, M., & MacHugh, D. E. (2024). Genomic insights into the population history and adaptive traits of Latin American Criollo cattle. Royal Society Open Science, 11(3), 231388. doi:10.1098/rsos.231388.

Hall, T. J., McHugo, G. P., Mullen, M. P., Ward, J. A., Killick, K. E., Browne, J. A., Gordon, S. V., & MacHugh, D. E. (2023). Integrative and comparative genomic analyses of mammalian macrophage responses to intracellular mycobacterial pathogens. Tuberculosis, 102453. doi:10.1016/j.tube.2023.102453.

Bhat, S. A., Elnaggar, M., Hall, T. J., McHugo, G. P., Reid, C., MacHugh, D. E., & Meade, K. G. (2023). Preferential differential gene expression within the WC1.1+ γδ T cell compartment in cattle naturally infected with Mycobacterium bovis. Frontiers in Immunology, 14, 1265038. doi:10.3389/fimmu.2023.1265038.

Correia, C. N., McHugo, G. P., Browne, J. A., McLoughlin, K. E., Nalpas, N. C., Magee, D. A., Whelan, A. O., Villarreal-Ramos, B., Vordermeier, H. M., Gormley, E., Gordon, S. V., & MacHugh, D. E. (2022). High-resolution transcriptomics of bovine purified protein derivative-stimulated peripheral blood from cattle infected with Mycobacterium bovis across an experimental time course. Tuberculosis, 136, 102235. doi:10.1016/j.tube.2022.102235.

Ward, J. A., McHugo, G. P., Dover, M. J., Hall, T. J., Ng’ang’a, S. I., Sonstegard, T. S., Bradley, D. G., Frantz, L. A. F., Salter-Townshend, M., & MacHugh, D. E. (2022). Genome-wide local ancestry and evidence for mitonuclear coadaptation in African hybrid cattle populations. iScience, 25(7), 104672. doi:10.1016/j.isci.2022.104672.

Hall, T. J., Mullen, M. P., McHugo, G. P., Killick, K. E., Ring, S. C., Berry, D. P., Correia, C. N., Browne, J. A., Gordon, S. V., & MacHugh, D. E. (2021). Integrative genomics of the mammalian alveolar macrophage response to intracellular mycobacteria. BMC Genomics, 22, 343. doi:10.1186/s12864-021-07643-w.

McHugo, G. P., Dover, M. J., & MacHugh, D. E. (2019). Unlocking the origins and biology of domestic animals using ancient DNA and paleogenomics. BMC Biology, 17, 98. doi:10.1186/s12915-019-0724-7.

McHugo, G. P., Browett, S., Randhawa, I. A. S., Howard, D. J., Mullen, M. P., Richardson, I. W., Park, S. D. E., Magee, D. A., Scraggs, E., Dover, M. J., Correia, C. N., Hanrahan, J. P., & MacHugh, D. E. (2019). A population genomics analysis of the native Irish Galway sheep breed. Frontiers in Genetics, 10, 927. doi:10.3389/fgene.2019.00927.

Browett, S., McHugo, G., Richardson, I. W., Magee, D. A., Park, S. D. E., Fahey, A. G., Kearney, J. F., Correia, C. N., Randhawa, I. A. S., & MacHugh, D. E. (2018). Genomic characterisation of the indigenous Irish Kerry cattle breed. Frontiers in Genetics, 9, 51. doi:10.3389/fgene.2018.00051.

Gillian McHugo's Projects

website icon website

files used to make my personal website

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