Comments (5)
eloyfelix
commented on July 18, 2024
5
sorry for the delayed reply. There was a networking issue in the EBI datacenter that affected our webservices. The issue is now solved with the help of the EBI networking team. The webservices and the webresource client should be working normally now.
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piehld
commented on July 18, 2024
3
From what I've observed, this appears to be due to intermittent downtime of https://www.ebi.ac.uk/chembl/api/data/molecule.json, in which case an error page ("500 internal server") is returned instead of the desired json. When the page is accessible, no errors occur.
I think it would be valuable if the chembl client was able to automatically re-try a given request if it returns a 500 internal server error rather than simply failing, since the server seems to come back up within several seconds of the initial server error.
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gorostiolam
commented on July 18, 2024
1
I am experiencing the same issue since last week when using any client functionality.
The main error message is:
chembl_webresource_client.http_errors.HttpApplicationError: Error for url https://www.ebi.ac.uk/chembl/api/data/molecule.json, server response: <!doctype html>
Followed by a very long HTML error message.
I am assuming this error is due to an update in the API for which the client has not caught up yet. Is there an estimated timeframe for solving this issue?
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David-Araripe
commented on July 18, 2024
Something seems to be wrong with the json response. The following snippet reproduces the same error reported:
from chembl_webresource_client.new_client import new_client
molecule = new_client.molecule
mols = molecule.filter(molecule_synonyms__molecule_synonym__iexact='viagra').only('molecule_chembl_id')
mols
I did a workaround by changing the url_query.py module, substituting line 40 from self.frmt = 'json' to self.frmt='xml'. After that, I could get the results without a problem by running this instead:
from chembl_webresource_client.new_client import new_client
molecule = new_client.molecule
mols = molecule.filter(molecule_synonyms__molecule_synonym__iexact='viagra').only('molecule_chembl_id')
mols.set_format(frmt='json')
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wen19shui
commented on July 18, 2024
Hi, when I queried the activity data related to plasma stability in chembl, I encountered the same problem. This is my error code:
HttpApplicationError: Error for url https://www.ebi.ac.uk/chembl/api/data/activity.json, server response: <!doctype html>
<!-- paulirish.com/2008/conditional-stylesheets-vs-css-hacks-answer-neither/ -->
<!--[if lt IE 7]> <html class="no-js ie6 oldie" lang="en"> <![endif]-->
<!--[if IE 7]> <html class="no-js ie7 oldie" lang="en"> <![endif]-->
<!--[if IE 8]> <html class="no-js ie8 oldie" lang="en"> <![endif]-->
<!-- Consider adding an manifest.appcache: h5bp.com/d/Offline -->
<!--[if gt IE 8]><!--> <html class="no-js" lang="en"> <!--<![endif]-->
<head>
Do you have any solutions to this. What bothers me is the lack of such data in other relevant places. Chembl is the only database where I can find relevant content, but it seems unstable recently. Thank you.
This is the code I used to query:
act_list = []
for assay_id in tqdm(Plasma_assayID_list[14:], 'Analying data for Plasma'):
activities = activity.filter(
assay_chembl_id=assay_id,
# relation="=", assay_type="B"
).only(
"assay_id",
"assay_description",
"molecule_chembl_id",
"canonical_smiles",
"document_chembl_id",
"standard_relation",
"standard_value",
"standard_units",
"standard_type",
"target_organism",
"target_pref_name"
)
for act in activities:
act_list.append(act)
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Related Issues (20)
- .filter for different names in "document_journal" column HOT 1
- Query hangs after reaching specific entry HOT 1
- Error for url https://www.ebi.ac.uk/chembl/api/data/activity.json, server response: <!doctype html> HOT 6
- Mechanism results do not match what is on the website HOT 3
- Isomeric SMILES string
- Problem with unichem.structure HOT 4
- Querying by inchi
- new_client is failing to import from chembl_webresource_client HOT 1
- Assay offsets and limit HOT 2
- How do I retrieve the Unichem Cross references as a dictionary/list for a CHEMBL compound?
- Fail to import new_client due to API problem HOT 5
- Fixed
- Space between words of the query
- HttpApplicationError HOT 8
- confidence score
- Error for url
- ChEMBL webresourse client issue
- status 500 with chembl_webresource_client.new_client
- Problem of parallelized big data mining via batch chunks
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